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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13410 | ZLDI-8 | Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related | |
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein. | |||
T22424 | 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea | Apoptosis , STAT | |
SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular ca... | |||
T9945 | MNK8 | 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione | STAT |
MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1]. | |||
T61184 | LQZ-7F | Apoptosis , Survivin | |
LQZ-7F is a small molecule survivin dimerisation inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation, mitotic arrest, and apoptosis, and blocks human tumour growth in mouse xenogra... | |||
T35610 | 2,5-dimethyl Celecoxib | Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor | |
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 μM) and reduces prostaglandin ... | |||
TP2292 | survivin (baculoviral IAP repeat-containing protein 5) (21-28) | Others | |
Survivin (baculoviral inhibitor of apoptosis IAP repeat-containing protein-5) is a member of the IAP gene family, which has been implicated in both inhibitions of apoptosis and mitosis regulation1. Survivin is one of the... | |||
T35542 | LLP-3 | ||
Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins. LLP-3 is a ... | |||
T70988 | Ibulocydine | ||
Ibulocydine is a potent CDK inhibitor. Ibulocydine has high activity against Cdk7/cyclin H/Mat1 and Cdk9/cyclin T. Ibulocydine inhibited the growth of HCC cells more effectively than other Cdk inhibitors, including olomo... | |||
T61030 | STAT3-IN-11 | Apoptosis , STAT | |
STAT3-IN-11 is a selective STAT3 inhibitor with inhibitory effects on phosphorylation of the STAT3pTyr705 site and phosphorylation of Survivin.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound fo... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3S1471 | Cucurbitacin IIA | Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA | Apoptosis , Survivin |
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00992 | BIRC5 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
BIRC5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-02532 | BIRC5 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
BIRC5 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.3 kDa and the accession number is O70201. | |||
TMPH-02533 | BIRC5 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
BIRC5 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is O70201. |